Skip Navigation
Department of Health and Human Services www.hhs.gov
 
This website is iPhone friendly.

This CME/CE activity is provided by PRIME Education, Inc. (PRIME®) and is accredited for a multi-disciplinary audience of health care practitioners. This activity is supported by contract number HHSA290201200021I from the Agency for Healthcare Research and Quality. User data collected through this activity will reside on PRIME's educational portal for use by AHRQ.

AHRQ's Comparative Effectiveness Research on Oral Medications for Type 2 Diabetes: A Summary of the Key Findings

Credit for this CME/CE activity has expired.

You can still access the program, but will not receive a certificate.

Program Overview

Activity Description

In recent years, the number of oral medications for people with type 2 diabetes has increased dramatically. More than 10 classes of oral agents are currently approved for use in the United States. This situation raises important questions for health professionals who treat and manage patients with type 2 diabetes. For controlling glycemia and preventing long-term complications of diabetes, are any agents better than others? How do oral medications compare with regard to risks of hypoglycemia, weight gain, gastrointestinal complications, congestive heart failure, and other adverse outcomes? What are the comparative benefits and risks of combination oral therapies? Evidence-based answers to these questions are available in a large-scale comparative effectiveness review that was commissioned by AHRQ and published in 2011. The findings and potential clinical applications are summarized in this accredited journal article.

Core Competencies:

  • Practice-based Learning and Improvement
  • Systems-based Practice
  • Interpersonal Skills and Communication
  • Medical Knowledge

Learning Objectives

At the conclusion of this activity, the participant should be able to:

  • Describe the comparative benefits of treatment options on intermediate measures of glycemic control and on long-term morbidity and mortality outcomes
  • Compare the harms of treatment options based on risks of adverse events including hypoglycemia, liver injury, congestive heart failure, severe lactic acidosis, and pancreatitis
  • Summarize the gaps in current knowledge regarding the comparative benefits and harms of treatment options across prespecified patient subpopulations

Target Audience

This CME activity is designed to meet the educational needs of physicians, pharmacists, nurses, and case managers.

Method of Participation

To receive a certificate for this activity, you should:

  • Complete the learner assessment pretest
  • View the entire activity online
  • Complete an online evaluation & post-test
  • Print your certificate online

The estimated time to complete this activity, including review of the materials, is 1.25 hours.

Term of Approval

January 30, 2012 through September 30, 2013. Original release date: January 30, 2012.

Acknowledgement of Support

There is no fee for this CME/CE activity. This activity is sponsored by PRIME Education, Inc (PRIME®) and funded under contract HHSA290201200021I from the Agency for Healthcare Research and Quality (AHRQ), U.S. Department of Health and Human Services (HHS).

Faculty Biographies and Disclosures

Click faculty name to view full biography.

Contributing Author

Wendy L Bennett, MD, MPH
Assistant Professor of Medicine
Population, Family and Reproductive Health
Bloomberg School of Public Health
Johns Hopkins Medicine
The Johns Hopkins University
Baltimore, MD

Contributing Author

Diana I Brixner, RPh, PhD
Professor and Chair Department of Pharmacotherapy
Executive Director of the Pharmacotherapy Outcomes Research Center
University of Utah College of Pharmacy
University of Utah
Salt Lake City, UT

Contributing Author

Joanne M Faysal, MS, C (ASCP)
Medical Writer II
PRIME Education, Inc.
Tamarac, FL

Contributing Author

Lisa Balfe, MPH
Medical Writer
PRIME Education, Inc (PRIME)

Planner

Heidi Wynn Maloni, PhD, ANP-BC, CNRN, MSCN
National Clinical Nursing Director
Department of Neurology
Multiple Sclerosis Center of Excellence
East Veterans Affairs Medical Center
Adjunct Faculty
Trinity Nursing Program School of Professional Studies
Trinity Washington University
Clinical Preceptor and Instructor
Advanced Practice Programs
The Catholic University of America School of Nursing
Washington, DC

Planner

Michele B Kaufman, PharmD, CGP, RPh
President, PRN Communications Inc.
Editor, Pharmacovigilance Forum, P&T Journal
NYCSHP Secretary
Adjunct Faculty
Touro College of Pharmacy
New York, NY

Peer Reviewer

Michael N Baxley, MD, MS, MPH
Chief of Quality Medical Initiative
MCCI Medical Group
Miami, FL
President and Founder Physician
AUK DOK
Managed Care Consulting Service Company
Miami, FL

Peer Reviewer

Debbie DeMuria, PharmD, RPh
Clinical Pharmacist
Consultant, Regulatory Affairs
Southborough, MA

Peer Reviewer

Kathleen A Jarvis, MS, RN, CCM
Clinical Educator
Alere Healthcare
Fort Lauderdale, FL

Begin Activity

Accreditation/Credit Designation

This program is no longer accredited.

Begin Activity

Faculty Disclosures

Faculty Name
Advisory Board Consultant Grants / Research Salary / Contractual Supported Promotional Education Stock / Shareholder Other Financial Support
Wendy L Bennett, MD, MPH
Contributor
None None None None None None None
Diana I Brixner, RPh, PhD
Contributor
Novo Nordisk None Novartis, Abbott None None None None
Joanne M Faysal, MS, C (ASCP)
Contributor
None None None None None None None
Lisa Balfe, MPH
Contributor
None None None None None None None
Heidi Wynn Maloni, PhD, ANP-BC, CNRN, MSCN
Planner
sanofi aventis None None None None None None
Michele B Kaufman, PharmD, CGP, RPh
Planner
None OrthoMcNeill Janssen None None None None None
Michael N Baxley, MD, MS, MPH
Reviewer
None None None None None None None
Debbie DeMuria, PharmD, RPh
Reviewer
None Millennium Pharmaceuticals, Inc None None None None None
Kathleen A Jarvis, MS, RN, CCM
Reviewer
None None None None None None None
Chris R Prostko, PhD
Scientific Program Director
NoneNoneNonePRIME®NoneNoneNone
Lynn Goldenberg, RN, BSN
Director of Accreditation & Compliance
NoneNoneNonePRIME®NoneNoneNone

Disclosure Policy

PRIME Education Inc (PRIME®) endorses the standards of the ACCME, as well as those of the AANP, ANCC and ACPE, that require everyone in a position to control the content of a CME/CE activity to disclose all financial relationships with commercial interests that are related to the content of the CME/CE activity. CME/CE activities must be balanced, independent of commercial bias and promote improvements or quality in healthcare. All recommendations involving clinical medicine must be based on evidence accepted within the medical profession.

A conflict of interest is created when individuals in a position to control the content of CME/CE have a relevant financial relationship with a commercial interest which therefore may bias his/her opinion and teaching. This may include receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, stocks or other financial benefits.

PRIME® willidentify, review and resolve all conflicts of interest that speakers, authors, course directors, planners, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for speakers, authors, course directors, planners, peer reviewers, and/or relevant staff are provided with this activity.

Presentations that provide information in whole or in part related to non FDA approved uses of drugs and/or devices will disclose the unlabeled indications or the investigational nature of their proposed uses to the audience. Participants should refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. Participants should verify all information and data before treating patients or employing any therapies prescribed in this educational activity. The opinions expressed in the educational activity are those of the presenting faculty and do not necessarily represent the views of PRIME®, the ACCME, AANP, ACPE, ANCC and other relevant accreditation bodies.

Content validation methods are consistently utilized by PRIME® to ensure that all program content is evidence-based, fair-balanced, and developed with scientific rigor and integrity. All clinical recommendations are based on evidence accepted within the medical profession. All scientific research referred to, reported or used to support a clinical recommendation conforms to accepted standards of experimental design, data collection and analysis. In addition to review of content by course directors and expert faculty, content is also validated through independent peer reviewers selected for their expertise in the content area, as well as their experience in the intended audience. All peer reviewers, planners, course directors, faculty and relevant staff utilized by PRIME® complete disclosures which are related to their role in the educational activity.

Accessibility

PRIME®is committed to providing access to our CME programs for individuals with disabilities as identified in Section 508 of the Rehabilitation Act for all web-based programs. This website is 508 compliant.

Begin Activity

1. Access the Activity:

Adobe Acrobat Reader or equivalent is required to view this program.

Download the P D F Activity
Open the PDF Activity in New Tab Open the PDF Activity in New Tab

Post-Test & Evaluation

Credit for this program has expired.

If you already completed this program and need to reprint your certificate(s), login here.

Clinician & Consumer Summaries on Premixed Insulin Analogues

Download these free summaries for your reference and/or patient handouts. You may also order bulk copies free of charge from the AHRQ Publication Clearinghouse below.

AHRQ Clearinghouse Bulk Order Form

Returning user? Login Here
  • (Limit 200)
  • (This answer helps stop spam )
  • Alternatively, you can call the AHRQ Publications Clearinghouse at 1-800-358-9295. Reference the title and product number above.