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This CME/CE activity is provided by PRIME Education, Inc. (PRIME®) and is accredited for a multi-disciplinary audience of health care practitioners. This activity is supported by contract number HHSA290201200021I from the Agency for Healthcare Research and Quality. User data collected through this activity will reside on PRIME's educational portal for use by AHRQ.

Summary of AHRQ's Comparative Effectiveness Review of Disease-Modifying Antirheumatic Drugs for Children with Juvenile Idiopathic Arthritis

Credit for this CME/CE activity has expired.

You can still access the program, but will not receive a certificate.

Program Overview

Activity Description

Juvenile idiopathic arthritis (JIA) is the most common rheumatologic childhood disease, affecting 7 to 400 out of 100,000 children. The debilitating physical and mental health burden of this chronic disease on affected children, combined with the stress placed on their families, underlies the need for comparative effectiveness research to determine the most beneficial and safe treatment interventions.

In 2011, the Agency for Healthcare Research and Quality (AHRQ) published a comparative effectiveness review on treatments for JIA, including synthetic and biologic DMARDs. The review systematically examines the scientific studies on available outcome measures for JIA. The synthesis of this information clarifies the available evidence and can guide clinicians and families in making appropriate treatment decisions. The findings and potential clinical applications of the AHRQ review are presented in this educational monograph.

Learning Objectives

At the conclusion of this activity, the participant should be able to:

  • Compare the effectiveness of conventional treatments versus newer synthetic or biologic disease-modifying anti-rheumatic drugs (DMARDs) for the following outcomes: symptoms, laboratory measures of inflammation, radiographic progression, and health status
  • Describe the comparative effectiveness of various DMARDs on key clinical, laboratory, and radiographic outcome measures
  • Summarize the rates and types of adverse events in comparisons between various DMARDs and between conventional treatments and DMARDs
  • Apply the review findings to making effective, patient-centered treatment and management decisions

Target Audience

This CME activity is designed to meet the educational needs of this cme activity is designed to meet the educational needs of physicians, pharmacists, nurses, and case managers.

Method of Participation

To receive a certificate for this activity, you should:

  • Complete the learner assessment pretest
  • View the entire activity online
  • Complete an online evaluation & post-test
  • Print your certificate online

The estimated time to complete this activity, including review of the materials, is 1.0 hour.

Term of Approval

March 01, 2012 through September 30, 2013. Original release date: March 01, 2012.

Acknowledgement of Support

There is no fee for this CME/CE activity. This activity is sponsored by PRIME Education, Inc (PRIME®) and funded under contract HHSA290201200021I from the Agency for Healthcare Research and Quality (AHRQ), U.S. Department of Health and Human Services (HHS).

Faculty Biographies and Disclosures

Click faculty name to view full biography.

Contributing Author

Robert McMahan, PharmD, MBA, MATS
Vice President, Clinical Pharmacy Operations
Amerigroup Corporation
Virginia Beach, VA


Contributing Author

Brandon Bellows, PharmD
Health Economics and Outcomes Research Fellow
Pharmacotherapy Outcomes Research Center
University of Utah College of Pharmacy
Salt Lake City, UT

Contributing Author

Laurence Greene, PhD
Scientific Education Manager
PRIME Education, Inc.
Tamarac, FL

Contributing Author

Lisa Balfe, MPH
Medical Writer
PRIME Education, Inc (PRIME)

Planner

Frank L Urbano, MD, FACP
Medical Director, Care Management
Albert Einstein Medical Center
Philadelphia, PA
Assistant Professor of Medicine
Cooper Medical School of
Rowan University
Camden, NJ

Planner

Heidi Wynn Maloni, PhD, ANP-BC, CNRN, MSCN
National Clinical Nursing Director
Department of Neurology
Multiple Sclerosis Center of Excellence, East Veterans Affairs Medical Center
Adjunct Faculty
Trinity Nursing Program School of Professional Studies, Trinity Washington University
Clinical Preceptor and Instructor
Advanced Practice Programs, The Catholic University of America School of Nursing
Washington, DC

Peer Reviewer

Donna M Chiefari, BSc (Pharm), PharmD, RPh, FASHP
Adjunct Faculty & Preceptor
Albany College of Pharmacy
Albany, NY

Peer Reviewer

Kathleen A Jarvis, MS, RN, CCM
Clinical Educator
Alere Healthcare
Fort Lauderdale, FL

Peer Reviewer

Michael N Baxley, MD, MS, MPH
Chief of Quality Medical Initiative
MCCI Medical Group
Miami, FL
President and Founder Physician
AUK DOK
Managed Care Consulting Service Company
Miami, FL

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Accreditation/Credit Designation

This program is no longer accredited.

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Faculty Disclosures

Faculty Name
Advisory Board Consultant Grants / Research Salary / Contractual Supported Promotional Education Stock / Shareholder Other Financial Support
Robert McMahan, PharmD, MBA, MATS
Contributor
None None None None None None None
Brandon Bellows, PharmD
Contributor
None None None None None None None
Laurence Greene, PhD
Contributor
None None None None None None None
Lisa Balfe, MPH
Contributor
None None None None None None None
Frank L Urbano, MD, FACP
Planner
None None None None None None None
Heidi Wynn Maloni, PhD, ANP-BC, CNRN, MSCN
Planner
Sanofi-Aventis None None None None None None
Donna M Chiefari, BSc (Pharm), PharmD, RPh, FASHP
Reviewer
None None None None None None None
Kathleen A Jarvis, MS, RN, CCM
Reviewer
None None None None None None None
Michael N Baxley, MD, MS, MPH
Reviewer
None None None None None None None
Chris R Prostko, PhD
Scientific Program Director
NoneNoneNonePRIME®NoneNoneNone
Lynn Goldenberg, RN, BSN
Director of Accreditation & Compliance
NoneNoneNonePRIME®NoneNoneNone

Disclosure Policy

PRIME Education Inc (PRIME®) endorses the standards of the ACCME, as well as those of the AANP, ANCC and ACPE, that require everyone in a position to control the content of a CME/CE activity to disclose all financial relationships with commercial interests that are related to the content of the CME/CE activity. CME/CE activities must be balanced, independent of commercial bias and promote improvements or quality in healthcare. All recommendations involving clinical medicine must be based on evidence accepted within the medical profession.

A conflict of interest is created when individuals in a position to control the content of CME/CE have a relevant financial relationship with a commercial interest which therefore may bias his/her opinion and teaching. This may include receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, stocks or other financial benefits.

PRIME® willidentify, review and resolve all conflicts of interest that speakers, authors, course directors, planners, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for speakers, authors, course directors, planners, peer reviewers, and/or relevant staff are provided with this activity.

Presentations that provide information in whole or in part related to non FDA approved uses of drugs and/or devices will disclose the unlabeled indications or the investigational nature of their proposed uses to the audience. Participants should refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. Participants should verify all information and data before treating patients or employing any therapies prescribed in this educational activity. The opinions expressed in the educational activity are those of the presenting faculty and do not necessarily represent the views of PRIME®, the ACCME, AANP, ACPE, ANCC and other relevant accreditation bodies.

Content validation methods are consistently utilized by PRIME® to ensure that all program content is evidence-based, fair-balanced, and developed with scientific rigor and integrity. All clinical recommendations are based on evidence accepted within the medical profession. All scientific research referred to, reported or used to support a clinical recommendation conforms to accepted standards of experimental design, data collection and analysis. In addition to review of content by course directors and expert faculty, content is also validated through independent peer reviewers selected for their expertise in the content area, as well as their experience in the intended audience. All peer reviewers, planners, course directors, faculty and relevant staff utilized by PRIME® complete disclosures which are related to their role in the educational activity.

Accessibility

PRIME®is committed to providing access to our CME programs for individuals with disabilities as identified in Section 508 of the Rehabilitation Act for all web-based programs. This website is 508 compliant.

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Post-Test & Evaluation

Credit for this program has expired.

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Clinician & Consumer Summaries on JIA

Download these free summaries for your reference and/or patient handouts. You may also order bulk copies free of charge from the AHRQ Publication Clearinghouse below.

AHRQ Clearinghouse Bulk Order Form

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  • Alternatively, you can call the AHRQ Publications Clearinghouse at 1-800-358-9295. Reference the title and product number above.